C1QA Antibody

• Background:

  C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca (2+) -dependent C1r (2) C1s (2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

• NCBI Gene ID:

  712

• Swiss Prot:

  P02745

• Accession Number:

  P02745

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This C1QA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 89-103 amino acids from the Central region of human C1QA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  C1QA

• NCBI Official Name:

  Complement C1q subcomponent subunit A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sellar G.C., et al.Biochem. J. 274:481-490 (1991) .

• Background Reference 02:

  Wan T., et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.

• Background Reference 03:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 04:

  Gregory S.G., et al.Nature 441:315-321 (2006) .

• Other Product Names:

  Complement C1q subcomponent subunit A, C1QA

• Tested Applications:

  WB

• Protein ID:

  399138

• Physical Properties:

  Liquid