C1QB Antibody

• Background:

  C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.

• NCBI Gene ID:

  713

• Swiss Prot:

  P02746

• Accession Number:

  P02746

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This C1QB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-81 amino acids from the N-terminal region of human C1QB.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  C1QB

• NCBI Official Name:

  Complement C1q subcomponent subunit B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Reid, K.B. et.al., Biochem. J. 173 (3), 863-868 (1978)

• Background Reference 02:

  Reid, K.B. et.al., Biochem. J. 179 (2), 367-371 (1979)

• Other Product Names:

  Complement C1q subcomponent subunit B, C1QB

• Tested Applications:

  WB, Flow

• Protein ID:

  298286922

• Physical Properties:

  Liquid