C1QA Antibody

• Background:

  C1QA is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on hromosome 1.

• NCBI Gene ID:

  712

• Swiss Prot:

  P02745

• Accession Number:

  P02745

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This C1QA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the C-terminal region of human C1QA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  C1QA

• NCBI Official Name:

  Complement C1q subcomponent subunit A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Dardiotis, E., Koutsou, P. J. Neurol. Sci. (2009) In press

• Background Reference 02:

  Martens, H.A., Zuurman, M.W. Ann. Rheum. Dis. 68 (5), 715-720 (2009)

• Background Reference 03:

  Racila, E., Link, B.K. Clin. Cancer Res. 14 (20), 6697-6703 (2008)

• Background Reference 04:

  Sjoberg, A.P., Nystrom, S. Mol. Immunol. 45 (11), 3213-3221 (2008)

• Other Product Names:

  Complement C1q subcomponent subunit A, C1QA

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  399138

• Physical Properties:

  Liquid