CPSF6 Antibody

• Background:

  CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

• NCBI Gene ID:

  11052

• Swiss Prot:

  Q16630

• Accession Number:

  NP_008938

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  61 kDa

• Applications Notes:

  CPSF6 antibody can be used for detection of CPSF6 by ELISA at 1:1562500. CPSF6 antibody can be used for detection of CPSF6 by western blot at 0.3125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CPSF6

• NCBI Official Name:

  Cleavage and polyadenylation specific factor 6, 68kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rual, J.F., (2005) Nature 437 (7062), 1173-1178.

• Other Product Names:

  CPSF6, CFIM, CFIM68, HPBRII-4, HPBRII-7

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  162329583

• Physical Properties:

  Liquid