CD1D Antibody

• Background :

  This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  912

• Swiss Prot :

  P15813

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human CD1D (NP_001757.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  Mouse liver

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 35kDa

• Fragment :

  IgG

• Symbol :

  CD1D

• NCBI Official Name :

  CD1d molecule

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CD1D, CD1D antigen, d polypeptide, R3, R3G1, CD1d antigen, CD1d molecule, Thymocyte antigen CD1D

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid