CD10 Antibody

• Background:

  Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

• NCBI Gene ID:

  4311

• Swiss Prot:

  P08473

• Accession Number:

  NP_000893.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  CD10 antibody was raised against a peptide sequence around aa.6~10 (S-Q-M-D-I) derived from Human CD10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  100 kDa

• Specificity:

  This antibody detects endogenous level of total CD10 protein.

• Applications Notes:

  Western Blot: 1:500

• Symbol:

  MME

• NCBI Official Name:

  Membrane metallo-endopeptidase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yandle T. G., Brennan S. O., Espiner E. A., Nicholls M. G., Richards A. M. Peptides 10:891-894 (1989) Rice G. I., Thomas D. A., Grant P. J., Turner A. J., Hooper N. M. Biochem. J. 383:45-51 (2004) Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G. J. Biol. Chem. 285:39819-39827 (2010)

• Other Product Names:

  NEP, SFE, CD10, CALLA, NEP, MME, MGC126681

• Tested Applications:

  WB

• Protein ID:

  116256329

• Physical Properties:

  Liquid