CD1A Antibody

CAT: 0223-57-104Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-104Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
NCBI Gene ID
909
Swiss Prot
P06126
Accession Number
P06126
Host
Rabbit
Reactivity
Human
Immunogen
This CD1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human CD1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Symbol
CD1A
NCBI Official Name
T-cell surface glycoprotein CD1a
NCBI Organism
Homo sapiens
Background Reference 01
Zeissig, S., et al. J. Clin. Invest. 120 (8) :2889-2899 (2010)
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Valencia, J., et al. J. Leukoc. Biol. 87 (3) :405-414 (2010)
Background Reference 04
Cernadas, M., et al. J. Immunol. 184 (3) :1235-1241 (2010)
Other Product Names
T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1a, CD1A
Tested Applications
WB, IHC-P
Protein ID
288558852
Physical Properties
Liquid

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