CD18 Antibody

• Background:

  This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  3689

• Swiss Prot:

  P05107

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 70-170 of human CD18 (NP_000202.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  U-937

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 100kDa

• Fragment:

  IgG

• Symbol:

  ITGB2

• Positive Control 2:

  Mouse thymus

• Positive Control 3:

  Mouse lung

• Positive Control 4:

  Rat thymus

• NCBI Official Name:

  Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid