CD19 Antibody

• Background:

  Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

• NCBI Gene ID:

  930

• Swiss Prot:

  P15391

• Accession Number:

  P15391

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CD19.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CD19

• NCBI Official Name:

  B-lymphocyte antigen CD19

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Deaglio, S., Blood 109 (12), 5390-5398 (2007)

• Background Reference 02:

  Bradbury, L.E., J. Immunol. 149 (9), 2841-2850 (1992)

• Background Reference 03:

  Kozmik, Z., Mol. Cell. Biol. 12 (6), 2662-2672 (1992)

• Other Product Names:

  B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  160332376

• Physical Properties:

  Liquid