CD1C Antibody

CAT: 0223-57-038Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-038Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
NCBI Gene ID
911
Swiss Prot
P29017
Accession Number
P29017
Host
Rabbit
Reactivity
Human
Immunogen
This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CD1C
NCBI Official Name
T-cell surface glycoprotein CD1c
NCBI Organism
Homo sapiens
Background Reference 01
Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) :
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Garzon, D., et al. Mol. Immunol. 47 (2-3), 253-260 (2009) :
Background Reference 04
Van Rhijn, I., et al. J. Exp. Med. 206 (6) :1409-1422 (2009)
Other Product Names
T-cell surface glycoprotein CD1c, CD1c, CD1C
Tested Applications
WB
Protein ID
143811371
Physical Properties
Liquid

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