PDE8A Antibody

• Background:

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5151

• Swiss Prot:

  O60658

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human PDE8A (NP_002596.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse testis

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 93kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PDE8A

• Positive Control 2:

  Mouse eye

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Rat testis

• NCBI Official Name:

  Phosphodiesterase 8A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PDE8A, Phosphodiesterase 8A, HsT19550

• Tested Applications:

  WB

• Physical Properties:

  Liquid