PDE8A Antibody

• Background :

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  5151

• Swiss Prot :

  O60658

• Host :

  Rabbit

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human PDE8A (NP_002596.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  Mouse testis

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 93kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  PDE8A

• Positive Control 2 :

  Mouse eye

• Positive Control 3 :

  Mouse liver

• Positive Control 4 :

  Rat testis

• NCBI Official Name :

  Phosphodiesterase 8A

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PDE8A, Phosphodiesterase 8A, HsT19550

• Tested Applications :

  WB

• Physical Properties :

  Liquid