Products for Research Use Only
RegisterLogin

PDE6A Antibody

CAT: 0223-23-277Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-23-277Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes the cyclic-GMP (cGMP) -specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
NCBI Gene ID
5145
Swiss Prot
P16499
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 656-860 of human PDE6A (NP_000431.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
BT-474
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 120kDa
Fragment
IgG
Symbol
PDE6A
Positive Control 2
Rat brain
NCBI Official Name
Phosphodiesterase 6A, cGMP-specific, rod, alpha
NCBI Organism
Homo sapiens
Other Product Names
PDE6A, Alpha-PDE, CGMP phosphodiesterase alpha, CGPR-A, PDE6alpha, PDE V-B1, PDEA, Phosphodiesterase 6a, RP43, GMP-PDE alpha
Tested Applications
WB, IHC
Physical Properties
Liquid

Related Products

CatalogName
30-114PDE9A Antibody
15-863PDE7A Antibody
58-952PDE7A Antibody
14-301PDE8A Antibody
48-315PDE8A Antibody
48-318PDE9A Antibody
42-501PDE1A Antibody
22-572PDE6B Antibody
16-968PDE6G Antibody
64-082PDE6C Antibody

Alternative Products

CatalogName
20R-PR082PDE6A antibody
MBS8307629-01Anti-PDE6A Antibody
RD267927A-01PDE6A Polyclonal Antibody
526797-01PDE6A

Popular Products