PDE7A Antibody

• Background:

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• NCBI Gene ID:

  5150

• Swiss Prot:

  Q13946

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 345-456 of human PDE7A (NP_002594.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 56kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PDE7A

• Positive Control 2:

  Mouse testis

• Positive Control 3:

  Rat brain

• Positive Control 4:

  Rat testis

• NCBI Official Name:

  Phosphodiesterase 7A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PDE7A, PDE7A1, PDE7A2, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, PDE7, HCP1, TM22

• Tested Applications:

  WB

• Physical Properties:

  Liquid