PDE7A Antibody

• Background :

  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• NCBI Gene ID :

  5150

• Swiss Prot :

  Q13946

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 345-456 of human PDE7A (NP_002594.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  Jurkat

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 56kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  PDE7A

• Positive Control 2 :

  Mouse testis

• Positive Control 3 :

  Rat brain

• Positive Control 4 :

  Rat testis

• NCBI Official Name :

  Phosphodiesterase 7A

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PDE7A, PDE7A1, PDE7A2, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, PDE7, HCP1, TM22

• Tested Applications :

  WB

• Physical Properties :

  Liquid