PDE7A Antibody

• Background:

  Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.

• NCBI Gene ID:

  5150

• Swiss Prot:

  Q13946

• Accession Number:

  Q13946

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PDE7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human PDE7A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PDE7A

• NCBI Official Name:

  High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care (2010) In press :

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 04:

  Pekkinen, M., et al. Bone 43 (1) :84-91 (2008)

• Other Product Names:

  High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, HCP1, TM22, PDE7A

• Tested Applications:

  WB

• Protein ID:

  3182958

• Physical Properties:

  Liquid