PDE3A Antibody

CAT: 0223-18-159Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-18-159Size:100 µL
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Background
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
5139
Swiss Prot
Q14432
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 125kDa
Fragment
IgG
Symbol
PDE3A
Positive Control 2
Mouse lung
Positive Control 3
Mouse heart
Positive Control 4
Mouse brain
NCBI Official Name
Phosphodiesterase 3A, cGMP-inhibited
NCBI Organism
Homo sapiens
Other Product Names
PDE3A, CGI-PDE-A, HcGIP2, Phosphodiesterase 3a, Phosphodiesterase isoform 3a, CGI-PDE, CGI-PDE A, CGIP2, HPDE-3A, Phosphodiesterase type 3A
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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