PDE8B Antibody

CAT: 0223-60-835Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-835Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD) . Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8622
Swiss Prot
O95263
Accession Number
O95263
Host
Rabbit
Reactivity
Mouse
Immunogen
This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
99 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PDE8B
NCBI Official Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
NCBI Organism
Homo sapiens
Background Reference 01
Horvath, A., et al. Thyroid 20 (4) :363-367 (2010)
Background Reference 02
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 03
Appenzeller, S., et al. Am. J. Hum. Genet. 86 (1) :83-87 (2010)
Background Reference 04
Shields, B.M., et al. J. Clin. Endocrinol. Metab. 94 (11) :4608-4612 (2009)
Other Product Names
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, HsPDE8B, Cell proliferation-inducing gene 22 protein, PDE8B
Tested Applications
WB
Physical Properties
Liquid

Related Products

CatalogName
58-534PDE1B Antibody
55-986PDE4B Antibody
56-074PDE1B Antibody
57-875PDE8A Antibody
56-179PDE3B Antibody
14-271PDE7B Antibody
18-502PDE1B Antibody
22-572PDE6B Antibody
42-925PDE4B Antibody
48-315PDE8A Antibody

Alternative Products

CatalogName
GWB-MX193DPDE8B Antibody
STJ502386Anti-PDE8B Antibody
BS77705-01PDE8B polyclonal antibody
E45M07064G-4PDE8B Antibody (Center)
MBS7113848-01PDE8B Antibody, FITC Conjugated
NBP1-71817Rabbit Polyclonal PDE8B Antibody
STJ502387Anti-PDE8B Antibody BIOTIN
abx031349-01Phosphodiesterase 8B (PDE8B) Antibody
OAAB15450-400ULPDE8B Antibody - middle region
A52754-50ULPDE8B Antibody, HRP conjugated

Popular Products