(E) -SI-2

• Description:

  (E) -SI-2 is an isomer of SI-2, an inhibitor of the steroid receptor coactivator SRC-3. SI-2 has anticancer activity and increases the number of cytotoxic immune cells in mice with breast cancer[1].

• Product Name Alternative:

  (E) -EPH 116

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319

• Target:

  Drug Isomer

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e-si-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C2=CC=CC=C2N=C1N/N=C(C3=CC=CC=N3)\C

• Molecular Formula:

  C15H15N5

• Molecular Weight:

  265.31

• Precautions:

  P264-P280-P302+P352-P305+P351+P338-P362+P364

• References & Citations:

  [1]Han SJ, et al. Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment. Breast Cancer Res. 2022 Oct 31;24 (1) :73.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [380537-35-9]