SI-2

• Target :

  Others|||Apoptosis|||Src

• Related Pathways :

  Apoptosis|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis

• Purity :

  0.984

• Bioactivity :

  SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1) . SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.

• Smiles :

  CN1C=2C(N=C1NN=C(C)C3=CC=CC=N3)=CC=CC2

• Molecular Formula :

  C15H15N5

• Molecular Weight :

  265.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  223788-33-8