(E) -SI-2

• Target:

  Others

• Related Pathways:

  Others

• Purity:

  0.998

• Bioactivity:

  (E) -SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.

• Smiles:

  CN1C=2C(N=C1N/N=C(\C)/C3=CC=CC=N3)=CC=CC2

• Molecular Formula:

  C15H15N5

• Molecular Weight:

  265.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  380537-35-9