Z-IETD-AFC

• UNSPSC Description:

  Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/z-ietd-afc.html

• Purity:

  99.78

• Solubility:

  H2O : 5 mg/mL (ultrasonic)

• Smiles:

  O=C1OC2=C(C(C(F)(F)F)=C1)C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC3=CC=CC=C3)=O)[C@H](CC)C)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=C2

• Molecular Weight:

  821.75

• References & Citations:

  [1]Boudard D, et al. Increased caspase-3 activity in refractory anemias: lack of evidence for Fas pathway implication. Leukemia. 2002;16(11):2343-2345.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  219138-02-0