Ac-DEVD-AFC [Caspase-3 Substrate (AFC)]

CAT: 0544-MBS566149-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0544-MBS566149-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Storage Conditions
For long term storage, store at -20 °C. Protect from light
Specificity
Fluorogenic substrate for caspase-3 (CPP32), with a Km=9.7uM) and related cysteine proteases. Sequence is based on PARP cleavage at Asp216 for caspase-3. Similar to Ac-DEVD-AMC but the AFC fluorophore has a greater Stokes' shift upon cleavage than AMC. Reaction can be monitored quantitatively or visually using a hand-held long-UV lamp and visualizing a blue to green shift in fluorescence upon cleavage. Ex.: 400nm, Em.: 505nm
Short Name
[Ac-DEVD-AFC]

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