Ac-DEVD-AFC [Caspase-3 Substrate (AFC)]
CAT:
544-MBS566149-01
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
![Ac-DEVD-AFC [Caspase-3 Substrate (AFC)] - image 1](/gentaur-product-1.webp)
Ac-DEVD-AFC [Caspase-3 Substrate (AFC)]
- Storage Conditions: For long term storage, store at -20 °C. Protect from light
- Specificity: Fluorogenic substrate for caspase-3 (CPP32), with a Km=9.7uM) and related cysteine proteases. Sequence is based on PARP cleavage at Asp216 for caspase-3. Similar to Ac-DEVD-AMC but the AFC fluorophore has a greater Stokes' shift upon cleavage than AMC. Reaction can be monitored quantitatively or visually using a hand-held long-UV lamp and visualizing a blue to green shift in fluorescence upon cleavage. Ex.: 400nm, Em.: 505nm
- Short Name: [Ac-DEVD-AFC]