BMS-902483

CAT: 0804-HY-120609Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-120609Size:1 Each
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Description
BMS-902483 is a quinuclidine-containing spirooxazolidine that is a partial agonist of the α7 nicotinic acetylcholine receptor (nAChR) . BMS-902483 improves cognitive ability in preclinical rodent models.[1].
CAS Number
[1192810-88-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bms-902483.html
Smiles
C12CCN(CC2)C[C@]13OC(NC4=CC5=C(C=CC=C5)C=N4)=NC3
Molecular Formula
C18H20N4O
Molecular Weight
308.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5, 3’-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure Activity Relationship.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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