GDC-9918

• Description :

  GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor[1].

• UNSPSC :

  12352005

• Target :

  JAK

• Type :

  Reference compound

• Related Pathways :

  Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/gdc-9918.html

• Smiles :

  O=C(C1=C2N=CC=CN2N=C1)NC3=CN(C)N=C3C4=CC(S(=O)(CCO)=O)=CC=C4OC(F)F

• Molecular Formula :

  C20H18F2N6O5S

• Molecular Weight :

  492.46

• References & Citations :

  [1]Dalton D M, et al. Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918[J]. Organic Process Research & Development, 2024, 28 (10) : 3858-3870.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2570375-06-1]