GDC-9918

• Description:

  GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor[1].

• UNSPSC:

  12352005

• Target:

  JAK

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gdc-9918.html

• Smiles:

  O=C (C1=C2N=CC=CN2N=C1) NC3=CN (C) N=C3C4=CC (S (=O) (CCO) =O) =CC=C4OC (F) F

• Molecular Formula:

  C20H18F2N6O5S

• Molecular Weight:

  492.46

• References & Citations:

  [1]Dalton D M, et al. Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918[J]. Organic Process Research & Development, 2024, 28 (10) : 3858-3870.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2570375-06-1