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HDAC3-IN-1

CAT: 0804-HY-117374-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117374-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].
CAS Number
2044701-99-5
Product Name Alternative
GMX1778
UNSPSC
12352005
Hazard Statement
H225-H319
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac3-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=CC=C1)NCC2=CC=C(C=C2)C(NNCCC)=O
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Moreno-Yruela C, Olsen CA. Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. ACS Med Chem Lett. 2022 Mar 16;13 (5) :779-785.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2; HDAC3

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