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HDAC3 degrader-1

CAT: 0013-GTR19274373-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274373-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC3degrader-1 (Compound Z8) is a selective HDAC3 degrader with a DC50 of 2.42 μM. It shows minimal impact on HDAC1, HDAC2, and HDAC6. By inhibiting the activation of the NLRP3 inflammasome, HDAC3degrader-1 reduces the secretion of IL-1β and caspase-1. It demonstrates significant efficacy in models of septic shock and colitis, making it valuable for anti-inflammatory research.
Storage Conditions
-20°C
Notes
For research use only.

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