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PROTAC SMARCA2 degrader-35

CAT: 0013-GTR19275121-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275121-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Compound PROTACSMARCA2 degrader-35 (Compound 43) acts as a selective degrader of SMARCA2 with a DC50 of less than 0.1 μM. It demonstrates anticancer properties by halting the cell cycle and inhibiting DNA replication in cancer cells lacking SMARCA4, thereby controlling their proliferation and growth.
CAS Number
3032998-97-0
Smiles
C (F) (F) [C@]12N (C=3C (NC1) =NN=C (C3) C4=C (O) C (F) =CC=C4) C[C@H] (OC5=CC=C (CN6CCN (CC6) C=7C=C8C (=CC7) CN (C8=O) [C@@H]9C (=O) NC (=O) CC9) C=N5) C2
Molecular Formula
C39H38F3N9O5
Molecular Weight
769.79
Storage Conditions
-20°C
Notes
For research use only.

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