P-gp-IN-30

CAT: 0013-GTR19263967-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19263967-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

P-gp-IN-30 (Compound 13) is an inhibitor of P-glycoprotein (P-gp) that targets YB-1. It reduces the expression of total YB-1 protein and nuclear YB-1 protein, thereby inhibiting the expression and function of downstream P-gp, which significantly enhances sensitivity to paclitaxel by inhibiting its efflux rate. When combined with paclitaxel, P-gp-IN-30 effectively suppresses tumor growth in A549/Taxol xenograft mouse models. This compound is useful for research on non-small cell lung cancer (NSCLC) .

CAS Number

2761881-65-4

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C (OCC) (=O) C1 (C (OCC) =O) [C@@]2 ([C@@H] ([C@H] (N1) C=3[C@@]4 ([C@] (CC3) (C (C (OC) =O) =CO[C@H]4OC) [H]) [H]) C5=CC=CC=C5) C=6C (NC2=O) =CC=CC6

Molecular Formula

C34H36N2O9

Molecular Weight

616.66

Storage Conditions

-20°C

Notes

For research use only.

Related Products

Catalog	Name
GTR19272890-01	P-gp-IN-32
GTR19264661-01	P-gp-IN-31
GTR19273727-01	P-gp-IN-33
GTR19184878-01	P-gp modulator 3
GTR19234794-01	P-gp inhibitor 17
GTR19258080-01	P-gp inhibitor 28
GTR19258034-01	P-gp inhibitor 29
GTR19266484-01	P-gp inhibitor 21
GTR19262653-01	P-gp modulator-4
GTR19262618-01	P-gp inhibitor 23

Alternative Products

Catalog	Name
HY-175206	P-gp-IN-30
HY-178349	P-gp inhibitor 30
HY-175522	P-gp-IN-31
HY-175838	P-gp-IN-32
HY-157484	P-gp inhibitor 19
HY-146117	P-gp modulator 2
HY-162447	P-gp inhibitor 22
T210177-01	P-gp/CDK2-IN-1
T210108-01	P-gp modulator-4
T207126-01	P-gp inhibitor 29

P-gp-IN-30

Related Products

Alternative Products

Popular Products