P-gp-IN-31

CAT: 0013-GTR19264661-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19264661-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

P-gp-IN-31 is an inhibitor of P-glycoprotein (P-gp) with IC50 values of 0.42 μM for KB cells and 0.43 μM for MDR KBvin cells. This compound effectively overcomes P-gp mediated drug efflux, exhibiting collateral sensitivity through P-gp downregulation. P-gp-IN-31 inhibits cell proliferation, induces apoptosis (apoptosis), and arrests the cell cycle in the G2/M phase. It is applicable in cancer research, particularly for multidrug-resistant (MDR) malignancies.

Field of Research

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

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HY-175522	P-gp-IN-31
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P-gp-IN-31

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