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PROTAC CDK2 Degrader-1

CAT: 0013-GTR19238814-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238814-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC CDK2 Degrader-1 (Compound 41) is a heterobifunctional molecule that selectively degrades CDK2. It demonstrates functional activity by inhibiting RB phosphorylation in OVCAR3 cells with an IC50 of 100-500 nM. This tool compound is used in vitro to study CDK2's role in cell cycle progression and oncology research.
CAS Number
3024971-78-3
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) CCN1C2=NN (C=3C=C (C=CC23) C4CCN (CC4) CC5CCN (CC5) S (=O) (=O) N6CCC (NC=7N=CC (=C (N7) C=8C=NN (C8) CC (F) (F) F) C (F) (F) F) CC6) C
Molecular Formula
C38H46F6N12O4S
Molecular Weight
880.91
Storage Conditions
-20°C
Notes
For research use only.

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