CDK2 degrader 1

• Bioactivity:

  CDK2 degrader1 (Compound 3) is an orally active cyclin-dependent kinase 2 (CDK2) degrader based on PROTAC technology. It binds to cerebellum, inducing ubiquitination of CDK2 followed by proteasomal degradation pathway. CDK2 degrader1 is utilized in the research of multiple cancers.

• Smiles:

  N(C(OC[C@H]1[C@]2(C[C@@](C1)(CC2)[H])[H])=O)C3CN(C3)C4=CC(F)=C(C(F)=C4)C5C(=O)NC(=O)CC5

• Molecular Formula:

  C23H27F2N3O4

• Molecular Weight:

  447.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3036604-59-5