EGFR-IN-133

CAT: 0013-GTR19240313-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19240313-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

EGFR-IN-133 (Compound 24) is a potent, orally bioavailable EGFR inhibitor effective against wild-type and multiple resistant mutations, including L858R/T790M and C797S variants, with IC50 values in the sub-nanomolar range. It is a valuable research tool for in vitro and in vivo studies exploring resistance mechanisms and therapeutic strategies in non-small cell lung cancer.

CAS Number

2809982-26-9

Field of Research

Cardiovascular Research, Cell Biology, Infectious Disease & Virology, Signal Transduction

Smiles

FC1=C2N3C (NC2=CC (N[C@@H]4CCOC4) =C1) =NC (=O) C=5C=C (C6=C (OCCC[C@@H] (C) C3) N (C) N=C6) N=C (F) C5

Molecular Formula

C27H29F2N7O3

Molecular Weight

537.56

Storage Conditions

-20°C

Notes

For research use only.

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T201790-01	EGFR-IN-133
C4664-10	RSC-133
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T34335-01	RM-133
T13772-01	MHP 133
HY-P6292	KS-133
T83956	CELT-133
HY-P1050-01	COG 133
464867-01	RSC 133

EGFR-IN-133

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