CELT-133

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  CELT-133 is a selective fluorescent antagonist for the h?1A adrenergic receptor, demonstrating complete selectivity towards ?1A over ?2A receptors, with a Ki of 5 nM and 15% displacement at 1 ?M in radioligand binding assays, respectively. It displays equivalent affinity across all ?1 adrenergic receptor subtypes. Notably, CELT-133 features excitation and emission maxima (?) at 560 and 571 nm, respectively, making it suitable for use as an acceptor dye in time-resolved Förster resonance energy transfer (TR-FRET) assays when paired with the CoraFluor 1 TR-FRET donor.

• Molecular Weight :

  1318.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C