Products for Research Use Only
RegisterLogin

CT-133

CAT: 0013-GTR19274884-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19274884-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CT-133 is a selective and potent antagonist of the CRTH2 Receptor, with a Ki value of 2.2 nM, and exhibits a Ki greater than 3800 nM for the DP1 receptor. It inhibits PGD2-induced neutrophil migration and significantly reduces lung inflammation and improves lung function impairment in a mouse model of acute lung injury (ALI) induced by cigarette smoke. Additionally, CT-133 effectively suppresses the overexpression of pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) and the chemokine (KC) while reversing the suppression of the anti-inflammatory factor IL-10. CT-133 is useful for ALI research.
CAS Number
2417155-47-4
Smiles
C (C (O) =O) C1=C2N (C=3C1=CC=CN3) C[C@H] (N (S (=O) (=O) C4=CC=C (F) C=C4) C) CC2.[Na]
Molecular Formula
C20H21FN3NaO4S
Molecular Weight
441.45
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19222850-01RM-133
GTR19200901-01RSC-133
GTR19273230-01ML-133
GTR19240313-01EGFR-IN-133
GTR19235080-01JE-133
GTR19154085-01COG 133
GTR19204283-01MHP 133
GTR19226893-01XY028-133
GTR19238432-01KS-133
GTR19219789CELT-133

Alternative Products

CatalogName
C4664-10RSC-133
B7941-5JWH 133
HY-106026YM 133
T201790-01EGFR-IN-133
T34335-01RM-133
T13772-01MHP 133
HY-P6292KS-133
T83956CELT-133
HY-P1050-01COG 133
464867-01RSC 133

Popular Products