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PROTAC SMARCA2 degrader-9

CAT: 0013-GTR19238685-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238685-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-9 (I-285) is a potent and selective degrader of the SMARCA2 protein. It demonstrates high efficacy in cellular models, such as A549 cells, achieving >90% degradation (DC50 <100 nM) within 24 hours, making it a valuable chemical probe for oncology and targeted protein degradation research.
CAS Number
2568276-39-9
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) N (C3=CC (=CC=C32) CCCN4CCN (C5=CN=C (N=C5) N6C7CN (C=8C=C (N=NC8N) C9=CC=CC=C9O) CC6CC7) CC4) C) CC1
Molecular Formula
C40H46N12O4
Molecular Weight
758.87
Storage Conditions
-20°C
Notes
For research use only.