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Antitumor agent-172

CAT: 0013-GTR19236411-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236411-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antitumor agent-172 is a potent small molecule inhibitor of the β-catenin/BCL9 protein-protein interaction (IC50 = 3.92 μM; Kd = 82 nM) . It demonstrates promising antitumor activity in murine models by disrupting oncogenic Wnt signaling, enhancing T cell activation and antigen presentation, as shown in published in vitro and in vivo studies.
CAS Number
3027905-74-1
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (CC1=CC=C (C=C1) C=2C=NNC2) (C (N[C@H]3CN (CCC3) C4=CC (OC (C (NCC (=O) N5C (CCN) CCC5) =O) (C) C) =CC=C4) =O) C6CC6
Molecular Formula
C37H50N8O4
Molecular Weight
670.84
Storage Conditions
-20°C
Notes
For research use only.

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