Products for Research Use Only
RegisterLogin

Antitumor agent-171

CAT: 0013-GTR19236353-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19236353-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antitumor agent-171 is a potent small molecule inhibitor of the β-catenin/BCL9 interaction (IC50=1.61 μM) with high affinity for β-catenin (Kd=0.63 μM) . It suppresses Wnt/β-catenin signaling downstream gene expression (Axin2 IC50=0.84 μM), inhibits cancer cell viability, and demonstrates in vivo antitumor activity alongside immunomodulatory effects such as T-cell activation.
CAS Number
3003004-76-7
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (CC1=CC=C (C=C1) C=2C=NNC2) (C (N[C@@H]3CN (CCC3) C4=CC (OC (C (NCC (=O) N5CC[C@H] (O) C5) =O) (C) C) =CC=C4) =O) C6CC6
Molecular Formula
C35H45N7O5
Molecular Weight
643.78
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19221274-01Antitumor agent-36
GTR19219034-01Antitumor agent-110
GTR19217788-01Antitumor agent-89
GTR19217787-01Antitumor agent-67
GTR19217786-01Antitumor agent-49
GTR19217781-01Antitumor agent-107
GTR19212727-01Antitumor agent-47
GTR19212726-01Antitumor agent-48
GTR19212710-01Antitumor agent-88
GTR19212705-01Antitumor agent-82

Alternative Products

CatalogName
HY-163767-01Antitumor agent-171
HY-163768-01Antitumor agent-172
HY-162128Antitumor agent-130
HY-161425Antitumor agent-149
HY-155034Antitumor agent-102
HY-151292Antitumor agent-74
HY-145289Antitumor agent-37
HY-146409Antitumor agent-59
HY-149717Antitumor agent-122
HY-115948Antitumor agent-46

Popular Products