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PROTAC ERα Degrader-10

CAT: 0013-GTR19241320-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241320-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC ERα Degrader-10 (Compound 160a) is a potent, orally active small molecule that degrades ERα with low nM DC50 values in breast cancer cell lines. It has shown promising in vivo antitumor efficacy in mouse models, supporting its use in oncology research for studying ERα-driven cancers and targeted protein degradation.
CAS Number
2421260-43-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (=C (/CC) \C1=CC=CC=C1) (\C2=CC=C (C=C2) N3CCC (CN4CCN (CC4) C=5C=C6C (=CC5) C (=O) N (C6) [C@@H]7C (=O) NC (=O) CC7) CC3) /C8=CC=C (O) C=C8
Molecular Formula
C45H49N5O4
Molecular Weight
723.9
Storage Conditions
-20°C
Notes
For research use only.

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