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PROTAC ERα Degrader-7

CAT: 0013-GTR19234723-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234723-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC ERα Degrader-7 (i-320) is a potent, heterobifunctional degrader of estrogen receptor alpha (ERα) with a DC50 of 6 pM. It employs a cereblon-binding ligand linked to an ERα-targeting moiety, facilitating the ubiquitination and proteasomal degradation of ERα. This tool compound is valuable for investigating ERα biology and therapeutic strategies in breast cancer research, both in vitro and in vivo.
CAS Number
3025781-93-2
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
FC1 (F) C[C@@H] ([C@@H] (C=2C1=CC (O) =CC2) C3=CC=C (C=C3) N4CCC (CN5CCN (CC5) C=6C=C7C (=CC6) C (=O) N (C7) [C@@H]8C (=O) NC (=O) CC8) CC4) C9=CC=C (C) C=C9
Molecular Formula
C46H49F2N5O4
Molecular Weight
773.91
Storage Conditions
-20°C
Notes
For research use only.

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