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PROTAC ERα Degrader-11

CAT: 0013-GTR19263188-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263188-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACERα Degrader-11 is a selective ERα PROTAC degrader with intrinsic fluorescence (Ex: 366 nm, Em: 440 nm) . It demonstrates strong anti-proliferative activity, selective ERα degradation, and fluorescence imaging capability in the MCF-7 breast cancer cell line. PROTACERα Degrader-11 induces G2/M phase arrest and apoptosis in MCF-7 cells. In athymic nude mice, it shows good safety with no acute toxic reactions at a dose of 500 mg/kg. PROTACERα Degrader-11 is suitable for breast cancer research.
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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