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SNIPER (ER) -110

CAT: 0013-GTR19224967-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19224967-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SNIPER (ER) -51 is a heterobifunctional degrader that targets the estrogen receptor (ER) for proteasomal degradation via cIAP1 recruitment. It demonstrates potent degradation with DC50 values below 10 nM in cellular assays. This compound is a valuable chemical tool for investigating targeted protein degradation in breast cancer and ER-related disease models.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C ([C@H]1N (C ([C@H] (C2CCCCC2) NC ([C@@H] (NC) C) =O) =O) C[C@@H] (OC3=CC=CC (OCCOCCOCCOCC (N (C) CCOC4=CC=C (/C (C5=CC=C (O) C=C5) =C (C6=CC=CC=C6) /CC) C=C4) =O) =C3) C1) N[C@@H]7CCCC8=C7C=CC=C8
Molecular Formula
C66H83N5O11
Molecular Weight
1122.39
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
T18696-01SNIPER (ER) -110
MBS5771555SNIPER(ER)-110
MBS3606946SNIPER (ER)-110
T18697SNIPER (ER) -87
7120/5SNIPER(ER)-87
BR1102Triple negative breast cancer (the most of TNBC) tissue array , including pathology grade, TNM, clinical stage (AJCC 8th edition) and IHC (ER/PR/Her-2) results, 110 cases/110 cores (core size 1.0mm)
BC081120gBreast cancer (including one case of male breast cancer) with adjacent normal breast tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition) with IHC results ER/PR/Her2/Ki67,110 cases/110 cores (core size 1.0 mm), replacing BC081120f
BC081116eBreast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type , breast carcinoma with apocrine differentiation and AT tissue, pathology grade, IHC ( ER/PR/Her-2/Ki67) info, TNM/Stage ( AJCC 7th edition), 107 cases/110 cores ( core size 1.5mm), replacing BC081116d-BC081116e
XND35429-01SNIPER (ABL) -039
XND35418-01SNIPER (ABL) -033

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