SNIPER (ER) -110

CAT: 0931-MF-0046571-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0046571-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||SNIPERs|||Estrogen Receptor/ERR
Related Pathways
Endocrinology/Hormones|||Others|||PROTAC
Bioactivity
SNIPER (ER) -110 comprises a cIAP1 ligand and an estrogen ligand connected by a linker. SNIPER (ER) -51 induces estrogen receptor (ER) protein degradation with DC50s of <3 nM and 7.7 nM after 4 h and 48 h, respectively [1].
Smiles
O=C([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)C[C@@H](OC3=CC=CC(OCCOCCOCCOCC(N(C)CCOC4=CC=C(/C(C5=CC=C(O)C=C5)=C(C6=CC=CC=C6)/CC)C=C4)=O)=C3)C1)N[C@@H]7CCCC8=C7C=CC=C8
Molecular Formula
C66H83N5O11
Molecular Weight
1122.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

CatalogName
MBS5771555SNIPER(ER)-110
MBS3606946SNIPER (ER)-110
M16952-01SNIPER (ER) -110
7120/5SNIPER(ER)-87
HY-129619SNIPER (ER) -87
BR1102Triple negative breast cancer (the most of TNBC) tissue array , including pathology grade, TNM, clinical stage (AJCC 8th edition) and IHC (ER/PR/Her-2) results, 110 cases/110 cores (core size 1.0mm)
BC081120gBreast cancer (including one case of male breast cancer) with adjacent normal breast tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition) with IHC results ER/PR/Her2/Ki67,110 cases/110 cores (core size 1.0 mm), replacing BC081120f
BC081116eBreast cancer with cancer adjacent breast tissue array, including invasive carcinoma of no special type , breast carcinoma with apocrine differentiation and AT tissue, pathology grade, IHC ( ER/PR/Her-2/Ki67) info, TNM/Stage ( AJCC 7th edition), 107 cases/110 cores ( core size 1.5mm), replacing BC081116d-BC081116e
MBS3847077-01SNIPER(CRABP)-11
M13419-01SNIPER (ABL) -062

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