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SNIPER (BRD) -1

CAT: 0013-GTR19226162-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19226162-01Size:25 mg
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Description
SNIPER (BRD) -1 is a heterobifunctional degrader molecule that links a derivative of the IAP antagonist LCL-161 to the BET inhibitor (+) -JQ-1. It induces potent degradation of BRD4 and IAP family proteins (cIAP1, cIAP2, XIAP) via the ubiquitin-proteasome system, serving as a valuable chemical probe for studying protein degradation and oncology research in cellular models.
CAS Number
2095244-54-3
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCCOC4=CC (C (=O) C=5N=C (SC5) [C@]6 (N (C ([C@@H] (NC ([C@@H] (NC) C) =O) C7CCCCC7) =O) CCC6) [H]) =CC=C4) =O) N=C2C8=CC=C (Cl) C=C8) =NN=C3C) SC1C
Molecular Formula
C53H66ClN9O8S2
Molecular Weight
1056.73
Storage Conditions
-20°C
Notes
For research use only.

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