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Keap1-Nrf2-IN-15

CAT: 0013-GTR19219486-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219486-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Keap1-Nrf2-IN-15 (Compound 24a) is a highly potent small molecule inhibitor that disrupts the Keap1-Nrf2 protein-protein interaction. It demonstrates potent activity in biochemical assays, with IC50 values of 77 nM (FP) and 2.5 nM (TR-FRET) . This inhibitor is a valuable research tool for investigating the Nrf2 pathway in oxidative stress and disease models, both in vitro and in vivo.
CAS Number
2456295-45-5
Field of Research
Cancer Biology, Immunology & Inflammation
Smiles
N (S (=O) (=O) C1=CC=C (OC) C=C1) (CC (O) =O) C=2C3=C (C (N (S (=O) (=O) C4=CC=C (OC) C=C4) CC (O) =O) =CC2CCCN5C (=O) C=6C (C5=O) =CC=CC6) C=CC=C3
Molecular Formula
C39H35N3O12S2
Molecular Weight
801.84
Storage Conditions
-20°C
Notes
For research use only.

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