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Keap1-Nrf2-IN-9

CAT: 0013-GTR19221103-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221103-01Size:5 mg
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Description
Keap1-Nrf2-IN-9 is a potent small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction (IC50 = 0.575 μM) . It activates the Nrf2 pathway, upregulating antioxidant genes like Hmox1 and Gclc in vitro, and shows no cytotoxicity in ARPE19 cells, making it a valuable research tool for studying oxidative stress and cytoprotection.
CAS Number
2769963-24-6
Field of Research
Cancer Biology, Immunology & Inflammation
Smiles
COc1ccc (cc1) S (=O) (=O) N (CC (O) =O) c1ccc (N (CC (O) =O) S (=O) (=O) c2ccc (OC) cc2) c (OCc2ccccc2) c1
Molecular Formula
C31H30N2O11S2
Molecular Weight
670.71
Storage Conditions
-20°C
Notes
For research use only.

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