Products for Research Use Only
RegisterLogin

Exatecan analog 36

CAT: 0804-HY-48878-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-48878-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Exatecan analog 36 is a analog of Exatecan. Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM).
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/exatecan-analog-36.html
Purity
98.71
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCC(C1=CC(N2C(C3=NC4=CC(F)=C(C)C5=C4C(C(NC(C)=O)CC5)=C3C2)=C1)=O)=O
Molecular Formula
C24H22FN3O3
Molecular Weight
419.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86 (8) :776-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins

Related Products

CatalogName
HY-178315Exatecan analog 38
HY-178290MC-Gly-Gly-Phe-Exatecan analog 38
HY-157795Exatecan analogue 1
HY-13631-01Exatecan
HY-156617-01Cyclopropaneacetamide-Exatecan
HY-160015-01CB07-Exatecan
HY-79490-01Ac-Exatecan
HY-13631A-01Exatecan (mesylate)
HY-13631R-01Exatecan (Standard)
HY-13631N(9R) -Exatecan

Alternative Products

CatalogName
T87728-01Exatecan analog 36
GTR19273502-01MC-Gly-Gly-Phe-Exatecan analog 38
T11249-01Exatecan
BA2357-1Decyclohexanamine-Exatecan
CS-O-47297Exatecan Hydroxyacid
FE72401-01Exatecan mesylate
T77901-01Ac-Exatecan
A11231-500Exatecan 500mg
A11231-25Exatecan 25mg
A11231-10Exatecan 10mg

Popular Products