Exatecan analog 36

• Target:

  ADC Cytotoxin|||Topoisomerase

• Related Pathways:

  DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Exatecan analog 36, an analog of Exatecan (DX-8951), is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 ?M) [1].

• Molecular Formula:

  C24H22FN3O3

• Molecular Weight:

  419.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C