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SOS1-IN-12

CAT: 0013-GTR19186233-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186233-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SOS1-IN-12 is a highly potent and selective SOS1 inhibitor, exhibiting sub-nanomolar affinity for SOS1 (Ki: 0.11 nM) and effectively suppressing pERK signaling (IC50: 47 nM) . This compound is a valuable chemical probe for investigating KRAS-driven cancers in both cellular and animal models, facilitating research into targeted oncology pathways.
CAS Number
2654741-56-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N ([C@H] (C) C1=C (C) C (C (F) (F) F) =CC=C1) C=2C3=C (C=CC (=C3) N4CCNCC4) C (C) =NN2
Molecular Formula
C23H26F3N5
Molecular Weight
429.48
Storage Conditions
-20°C
Notes
For research use only.

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