Products for Research Use Only

SOS1-IN-22

CAT: 0013-GTR19273093-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273093-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SOS1-IN-22 is an inhibitor of the non-heptakinase homologue (SOS1) . It effectively prevents the formation of the KRAS-G12C/SOS1 complex with an IC50 value of 40.28 nM. Additionally, SOS1-IN-22 reduces the phosphorylation levels of ERK. This compound is applicable in cancer research, including studies on pancreatic and appendiceal cancers.
CAS Number
3092445-74-1
Smiles
N ([C@H] (C) C1=C (F) C (C (F) F) =CC=C1) C2=C3C (C (C) (C) C (=O) N (C3) C4CCOCC4) =NC (C) =N2
Molecular Formula
C24H29F3N4O2
Molecular Weight
462.52
Storage Conditions
-20°C
Notes
For research use only.