BIO-32546

• Description :

  BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC50: 1 nM), extracted from the patent US20170158687A1[1].

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/bio-32546.html

• Purity :

  99.05

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  FC(F)(C1=C(O[C@@H]2CC[C@@H](CC2)C(F)(F)F)C=CC3=C1C=C([C@@H](N4C5CC(CC4CC5)C(O)=O)C)C=C3)F

• Molecular Formula :

  C28H31F6NO3

• Molecular Weight :

  543.54

• References & Citations :

  [1]Kevin M. Guckian, et al. Atx modulating agents. Patent. US20170158687A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Autotaxin

• CAS Number :

  [1548743-66-3]