CDK4/6-IN-20

• UNSPSC Description:

  CDK4/6-IN-20 (Compound II-5) is a CDK4/CDK6 inhibitor with IC50 values ​​of 1.9, 14.2 nM, respectively. CDK4/6-IN-20 also inhibits cell proliferation and can be used in cancer research[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cdk4-6-in-20.html

• Smiles:

  O[C@@H]1COCC[C@H]1NC2=NC=C(C#N)C(C3=CC(C4(CCCC4)C(C)=N5)=C5C(F)=C3)=N2

• Molecular Weight:

  421.47

• References & Citations:

  [1]HU, Pu, et al. 2-aminopyrimidine compound, and use and pharmaceutical composition thereof.WO2024066986A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3033950-84-1